| Date | Location | Result | |
| 3/02/01 | Roanoke, VA (Roanoke Civic Center) | Radford 65, Charleston Southern 62 | Box score |
| 3/01/01 | Roanoke, VA (Roanoke Civic Center) | Charleston Southern 77, Coastal Carolina 64 | Box score |
| 2/24/01 | N.Charleston, SC (CSU Fieldhouse) | Coastal Carolina 88, Charleston Southern 77 | Box score |
| 2/22/01 | N.Charleston, SC (CSU Fieldhouse) | Charleston Southern 64, North Carolina-Asheville 60 | Box score |
| 02/17/01 | Rock Hill, SC | Winthrop 76, Charleston Southern 51 | Box score |
| 2/15/01 | N.Charleston, SC (CSU Fieldhouse) | Virginia Military Institute 63, Charleston Southern 57 | Box score |
| 02/12/01 | High Point, North Carolina | Charleston Southern 63, High Point 58 | Box score |
| 2/10/01 | Elon College, NC (Alumni Gym) | Charleston Southern 67, Elon College 64 | Box score |
| 1/05/01 | N.Charleston, SC (CSU Fieldhouse) | Charleston Southern 82, Liberty 81 | Box score |
| 1/3/01 | N.Charleston, SC (CSU Feildhouse) | Radford 61, Charleston Southern 59 | Box score |
| 2/1/01 | N.Charleston, SC (CSU Fieldhouse) | Charleston Southern 58, Winthrop 55 | Box score |
| 1/29/01 | N.Charleston, SC (CSU Fieldhouse) | Charleston Southern 56, Birmingham Southern 55 | Box score |
| 1/26/01 | Conway, SC (Kimbel Arena) | Coastal Carolina 74, Charleston Southern 72 | Box score |
| 1/22/01 | N. Charleston,S.C (CSU Fieldhouse) | Elon College 68, Charleston Southern 65 | Box score |
| 1/20/01 | N. Charleston, SC (CSU Fieldhouse) | Charleston Southern 59, High Point 47 | Box score |
| 01/15/01 | Radford, Va. (Dedmon Center) | Radford 74, Charleston Southern 71 | Box score |
| 01/13/01 | Lynchburg, Va (Vines Center) | Liberty 70, Charleston Southern 57 | Box score |
| 01/10/01 | Aheville, N.C/Justice Center | North Carolina-Asheville 72, Charleston Southern 65 | Box score |
| 01/06/01 | CSU Fieldhouse Charleston, SC | Charleston Southern 90, Anderson College 88 | Box score |
| 12/28/00 | Clemson University | Clemson 87, Charleston Southern 77 | Box score |
| 12/21/00 | Kresse Arena | Jacksonville State 81, Charleston Southern 68 | Box score |
| 12/20/00 | Charleston, Kresse Arena | Delaware 82, Charleston Southern 31 | Box score |
| 12/06/00 | Charlotte, NC | Charlotte 88, Charleston Southern 46 | Box score |
| 12/02/00 | N.Charleston, S.C. | Charleston Southern 72, Brewton-Parker 64 | Box score |
| 11/29/00 | Greenville, S.C. | Furman 69, Charleston Southern 59 | Box score |
| 11/25/00 | Raleigh, N.C | N.C. State University 89, Charleston Southern 51 | Box score |
| 11/21/00 | Alexander Memorial Coliseum | Georgia Tech 85, Charleston Southern 62 | Box score |
| 11/27/00 | N.Charleston, SC | Stetson 85, Charleston Southern 59 | Box score |
| 11/17/00 | Charleston (North Charleston Coliseum) | College Of Charleston 73, Charleston Southern 52 | Box score |